As an interdisciplinary museum, the collections are wide ranging and include significant holdings in American folk art, works on paper, works created by art practitioners with connections to Northeast Pennsylvania, rocks, minerals, birds, plants, and Dorflinger glass. Only a small percentage of the collection is ever on view at a time.
The Everhart offers holdings of African, American, Asian, European and contemporary art as well as design arts and spans different time periods and cultures. The collections comprise paintings, sculpture, decorative, industrial, prints, drawings, photographs, as well as textiles.
The Museum was founded by Dr. Everhart primarily due to his fascination with Ornithology. As a result, the Museum has an extensive collection of birds from the Northeastern Pennsylvania region. The natural history collection also contains mammals, rocks, fossils, minerals, plant specimens, shell, and coral.